A team of scientists, led by an emerging Japanese pharmaceutical company, works on a drug to stimulate the growth of new teeth, while it may be the first of its kind in the world, with the aim of offering it in the market by almost 2030, according to the Gaban Times website and the ABC Australia.
Tergim Biovarma, funded by Kyoto University, is expected to start clinical trials on healthy adults in July 2024 to ensure the safety of the drug, after the team succeeded in cultivating new teeth in mice in 2018.
Most people have ‘teeth buds’ have the ability to become new teeth, as well as lactic and permanent teeth, although buds usually do not develop and disappear later
The team has invented a property that inhibits the protein that prevents the growth of teeth, works on these buds and stimulates its growth.
The team plans to conduct a clinical trial of the drug as of 2025 for children between the ages of two and 6 years who suffer from dental loss and are born without some or all the permanent teeth, and children will be injected with a single dose to stimulate the growth of teeth.
There are also hopes for the use of the drug in the future for adults who lost their teeth due to caries.
The teeth are erupted in two groups, the first is the milky teeth that soon fall to the second group, which is the permanent teeth. The health of the teeth and its supportive tissues (such as gums and al -Sunakhi bone) is an important thing for a person’s health and his health on the physical and psychological levels.
Parts of the inner tooth
- The enamel layer: It is the outer layer and is the harshest part of the human body, in which the concentration of minerals rises, and it mainly consists of ‘hydroxy Apattite’, which is a crystal pattern of calcium phosphate.
- Ivory layer: It is the second layer of tooth and is topped by the ‘enamel’ layer. The ivory color is yellow, which is less powerful than enamel, and the concentration of minerals is also less. It protects the pulp, and forms a pillar of the enamel layer and the crown of the tooth.
- The pulp: It is located under ivory and forms the inner age room, and it contains blood vessels that transmit oxygen, nourishing substances, and nerves that transmit nerve signals and sensations from tooth to the brain.
- Mortality: It is a yellow layer that surrounds the root of the tooth, and is associated with the alveolar bone through connective tissues. The gums of the gums as a result of inflammation, for example, lead to its disclosure, which may lead to the allergy of the tooth and the occurrence of caries in the root in some cases.
- Al Jazeera + websites